Prevention Strategies:
- Control blood sugar and insulin resistance:
- Keep fasting glucose below 90 mg/dL
- Keep fasting insulin below 5
- Consider low glycemic diet and building muscle
- Reduce inflammation:
- Test hsCRP and homocysteine
- Optimize omega-3 intake (DHA/EPA)
- Reduce stress, processed foods, and seed oils
- Protect brain energy metabolism:
- Consider ketogenic approaches or intermittent fasting
- Try exogenous ketones or MCT oil
- Optimize sleep and stress:
- Focus on quality deep sleep (last 4 hours most important)
- Support glymphatic system function (brain's cleaning system)
- Reduce blue light and stress before bed
These strategies work best when implemented early (30s-50s) and maintained consistently, as Alzheimer's pathology begins decades before symptoms appear.